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A new Xbox One controller released alongside the forthcoming The Rise of the Tomb Raider
Announced during Microsoft's E3 conference, the DualShock 4 controller should be available to purchase starting June 10. Priced at $69.99, the new controller comes with the usual array of features found on more recent Xbox One controllers, such as the touchpad and motion sensing.The new controller is a significant departure from its Sony counterpart, however. Not only does it support rumble again, but it features a braided cable and a redesigned thumbstick.There have been some reports that the new controller might be on the way for the PS4, though these seem to be unfounded.A leaked image of a box (below), has appeared, supposedly containing the new controller. No information on price or release date has yet been revealed."Other than a rumble motor and an external power switch, all other parts of the circuit board have been replaced," Microsoft explained.If you're looking to get your hands on the new Xbox One controller, we'll have a guide on how to setup the controller in your Xbox One and Titanfall 2, when the game launches on June 14.
Luke Karmali is IGN's UK Junior Editor. You too can revel in mediocrity by following him on TwitterA novel approach for studying synaptic plasticity in rat hippocampal slices.
In the present study, we provide a novel approach to study synaptic plasticity in the hippocampus. This consists in the use of small extracellular electrodes (2 μm tip diameter) positioned in CA1 stratum oriens to electrically stimulate Schaffer collaterals and monitor the frequency of EPSCs recorded in CA1 pyramidal cells. This approach allowed us to obtain reliable EPSCs frequency in a constant range of physiological conditions in both acute and long-term chronic slices, and it is well suited to record the effect of theta-burst stimulation (TBS) on plasticity. Here we show that this novel approach for monitoring synaptic plasticity is a valid and reliable tool to investigate the effect of TBS on synaptic transmission and plasticity. Furthermore, the study of synaptic plasticity is not altered by using this approach instead of the conventional whole-cell patch clamp.[Endobronchial recurrence